Chemistry
315 Organic Chemistry
Lab
I
Spring 2020
This
syllabus can be found at http://mason.gmu.edu/~sslayden/Lab/index.html
REVISED 4/27/2020 (revisions are shown in red, below)
Important
additional course information is found on the CHEM 315 section of BlackBoard.
Lab Text: J. R. Mohrig, D. G. Alberg,
G. E. Hofmeister, P. F. Schatz, and C. N. Hammond, Laboratory
Techniques in Organic Chemistry, 4th edition (2014).
Lab Manual: S. W. Slayden, R. J. Roth, and W. M.
Stalick, Laboratory Manual: Organic Chemistry 315, 318 (green cover).
Lecture Text: David Klein, Organic Chemistry, 3rd
edition.
Videos: Most viewing assignments can be found at
https://ocw.mit.edu/resources/res-5-0001-digital-lab-techniques-manual-spring-2007/videos
(MIT OpenCourseWare Creative Commons license).
PowerPoint files: Additional notes are posted on BlackBoard for each laboratory.
CHEM 313 lecture is a pre- or co-requisite for CHEM 315 lab. If you previously took CHEM 313, you must have earned at
least a C to use it as a pre-requisite for Chem 315. If you drop
or withdraw from CHEM 313, you must also drop/withdraw from CHEM 315.
Add, Drop, and Selective Withdrawal deadlines can be
found at http://registrar.gmu.edu.
It
is the responsibility of all students to be familiar with and adhere to the
GMU Honor Code. Please see https://oai.gmu.edu/.
If you are a student with a disability and you need academic
accommodations, please contact Disability Services at 993-2474, http://ds.gmu.edu.
All academic accommodations must be arranged through Disability Services.
Course Schedule
Lab Date |
Experiment Title |
Reading/Viewing Assignment |
Report Due |
Lab 1
Jan 21-27 |
Introduction and
safety; check-in; citing information for the laboratory |
Lab Manual pp.
1-20
Mohrig ch. 1 (omit 1.6, 1.7) |
Reports are due on the dates shown below.
|
Lab 2
Jan 28-Feb 3 |
Melting point |
Lab Manual pp.
23-25
Mohrig ch. 3.1, 3.3; 14
M
Pt video
|
Safety Quiz on Bb |
Lab 3
Feb 4-10 |
Recrystallization |
Lab Manual pp
27-31
Mohrig ch. 15 (pp. 221-230, 234-235); ch.
9 (pp. 132, 137-138, 140-142)
Recrystallization
video (0-14:38
min)
|
Melting Point
|
Lab
4
Feb 11-17 |
Thin layer
chromatography (TLC);
Recrystallization, cont'd. |
Lab Manual pp.
33-38
Mohrig pp. 127-131, 253-254; ch. 18
TLC
video
|
|
Lab
5
Feb 18-24 |
I. Gas
chromatography: alkyl acetates mixture
II. Refractive
index |
I. Lab Manual pp.
39-43
Mohrig ch. 20 (except 20.8 - see
Manual explanation)
GC
video 1; GC video 2
II. Lab Manual
pp. 45-47 (except Procedure steps 1 and 2b; Fig. 1; Table 1)
Mohrig ch. 13
|
Recrystallization |
Lab 6
Feb 25-Mar 2
|
Infrared and
ultraviolet-visible spectroscopy; mass spectrometry |
Lab Manual pp.
49, 53-56
Mohrig ch. 21 (21.1-21.2, 21.7-21.9); ch.
25 (pp 465-470); ch. 24 |
TLC |
Lab 7
Mar 3-7, 16 23 |
Identification
of an unknown; simple distillation to determine boiling point; IR continued
Spring Break March 9-22 |
Lab Manual pp.
49-51 Experiment pdf
Mohrig ch. 12 (pp
173-174, 176-183); ch. 21 (21.3-21.5, 21.10-21.11)
Simple Distillation
video (0-8:41 min); IR sample prep video
|
GC Acetates (new Report Form)
[Ref. Index not required]
See Bb for exact due date.
|
Lab 8
Mar 17-23Mar 24-30
|
Note: Lab Week is Tues.-Mon. |
|
Spectroscopy Assignment
Identification
of Unknown
See Bb for exact due date. |
Lab 9
Mar 30-Apr 4
|
Note: Lab Week is Mon. -Sat.
All LabFlow assignments begin on Monday for all sections.
LabFlow
Chemistry Math, Labware Kit Review |
via LabFlow |
All LabFlow work will be due the following Monday.
|
Lab 10
Apr 6-11
|
LabFlow
Identifying Unknowns using IR |
via LabFlow |
Chemistry Math, Labware Kit Review |
Lab 11
Apr 13-18
|
LabFlow
Identification of an Unknown Alcohol
|
via LabFlow |
Identifying Unknowns using IR |
Lab 12
Apr. 20-25
|
LabFlow
Extraction of Caffeine
|
via LabFlow |
Identification of an Unknown Alcohol |
Lab 13
Apr. 27-May 2
|
Fractional Distillation |
via LabFlow
|
Extraction of Caffeine |
Lab 14
May 5 (Tues.)-May 11 (Mon.)
|
Final Exam - see Bb for information |
|
Fractional Distillation (Due by Mon., May 4) |
|