Chemistry 315          Organic Chemistry Lab I                        Summer 2019

This syllabus can be found at

Important additional course information is found on the CHEM 315 section of BlackBoard.

Lab Text: J. R. Mohrig, D. G. Alberg, G. E. Hofmeister, P. F. Schatz, and C. N. Hammond, Laboratory Techniques in Organic Chemistry, 4th edition (2014).

Lab Manual: S. W. Slayden, R. J. Roth, and W. M. Stalick, Laboratory Manual: Organic Chemistry 315, 318 (2017).

Lecture Text: T. W. G. Solomons, C. B. Fryhle, and S. A. Snyder, Organic Chemistry, 12th edition (2016).

Videos: Most viewing assignments can be found at
(MIT OpenCourseWare Creative Commons license).

CHEM 313 lecture is a pre- or co-requisite for CHEM 315 lab. If you previously took CHEM 313, you must have earned at least a C to use it as a pre-requisite for Chem 315. If you drop or withdraw from CHEM 313, you must also drop/withdraw from CHEM 315.

Add, drop, and selective withdrawal deadlines can be found at

It is the responsibility of all students to be familiar with and adhere to the GMU Honor Code.

If you are a student with a disability and you need academic accommodations, please contact Disability Services at 993-2474, All academic accommodations must be arranged through Disability Services.

Course Schedule

Lab Date

Experiment Title

Reading/Viewing Assignment

Report Due

Lab 1

May 20

Introduction and safety; check-in; citing information for the laboratory

Lab Manual pp 1-20
Mohrig ch 1 (omit 1.6, 1.7)


Lab 2

May 22

Melting point

Lab Manual pp 23-25
Mohrig ch 3.1, 3.3; 14

M Pt video


Lab 3

May 24


Lab Manual pp 27-31
Mohrig ch 15 (221-230, 234-235); ch 9 (pp 132, 137-138, 140-142)

Recrystallization video (0-14:38 min)

Melting Point

Lab 4

May 29

Thin layer chromatography (TLC);
Recrystallization, cont'd.

Lab Manual pp 33-38
Mohrig pp 127-131, 253-254; ch 18

TLC video


Lab 5

May 31

I. Gas chromatography: alkyl acetates mixture



II. Refractive index

I. Lab Manual pp 39-43
Mohrig ch 20 (except 20.8 - see Manual explanation)

GC video 1; GC video 2

II. Lab Manual pp 45-47
Mohrig ch 13


Lab 6

June 3

Infrared and ultraviolet-visible spectroscopy; mass spectrometry

Lab Manual pp 49, 53-56
Mohrig ch 21 (21.1-21.2, 21.7-21.9); ch 25 (pp 465-470); ch 24



Lab 7

June 5

Identification of an unknown; simple distillation to determine boiling point; IR continued

Lab Manual pp 49-51
Mohrig ch 12 (pp 173-174, 176-183); ch 21 (21.3-21.5, 21.10-21.11)

Distillation video (0-8:41 min); IR sample prep video

GC Acetates

Lab 8

June 7

Fractional distillation

Lab Manual pp 59-63 [Disregard sections pertaining to Simple Distillation.]

Mohrig ch 12 (12.4, 12.8)

Distillation video (8:41-11:22 min)

Identification of Unknown

Lab 9

June 10

Extraction of caffeine

Lab Manual pp 67-70
Mohrig ch 10 (10.1 [except pp. 144-146], 10.3-10.5, 10.7); ch 11 (11.1-11.3); p. 321 (IR cast film)

Extraction video (0-11:25, 14:30-16:40 min)

Fractional distillation

Lab 10

June 12

Gas chromatography: analysis of distillate

Lab Manual pp 65-66
Mohrig ch 20

Extraction of caffeine

Lab 11

June 14

Qualitative organic analysis: alkanes, alkenes, alkynes, aromatics, alkyl & aryl halides, alcohols

Lab Manual pp 75-88

GC of distillate

Lab 12

June 17

Qualitative organic analysis continued


Lab 13

June 19

Synthesis of tert-pentyl chloride

Lab Manual pp 71-73
Mohrig ch 3.2; ch 10.2

Qualitative analysis

Lab 14

June 21

Final exam (Location TBD)


Synthesis of tert-pentyl chloride