Chemistry 315          Organic Chemistry Lab I                        Spring 2020

This syllabus can be found at

REVISED 4/27/2020 (revisions are shown in red, below)

Important additional course information is found on the CHEM 315 section of BlackBoard.

Lab Text: J. R. Mohrig, D. G. Alberg, G. E. Hofmeister, P. F. Schatz, and C. N. Hammond, Laboratory Techniques in Organic Chemistry, 4th edition (2014).

Lab Manual: S. W. Slayden, R. J. Roth, and W. M. Stalick, Laboratory Manual: Organic Chemistry 315, 318 (green cover).

Lecture Text: David Klein, Organic Chemistry, 3rd edition.

Videos: Most viewing assignments can be found at
(MIT OpenCourseWare Creative Commons license).

PowerPoint files: Additional notes are posted on BlackBoard for each laboratory.

CHEM 313 lecture is a pre- or co-requisite for CHEM 315 lab. If you previously took CHEM 313, you must have earned at least a C to use it as a pre-requisite for Chem 315. If you drop or withdraw from CHEM 313, you must also drop/withdraw from CHEM 315.

Add, Drop, and Selective Withdrawal deadlines can be found at

It is the responsibility of all students to be familiar with and adhere to the GMU Honor Code. Please see

If you are a student with a disability and you need academic accommodations, please contact Disability Services at 993-2474, All academic accommodations must be arranged through Disability Services.

Course Schedule

Lab Date

Experiment Title

Reading/Viewing Assignment

Report Due

Lab 1

Jan 21-27

Introduction and safety; check-in; citing information for the laboratory

Lab Manual pp. 1-20

Mohrig ch. 1 (omit 1.6, 1.7)

Reports are due on the dates shown below.

Lab 2

Jan 28-Feb 3

Melting point

Lab Manual pp. 23-25

Mohrig ch. 3.1, 3.3; 14

M Pt video

Safety Quiz on Bb

Lab 3

Feb 4-10


Lab Manual pp 27-31

Mohrig ch. 15 (pp. 221-230, 234-235); ch. 9 (pp. 132, 137-138, 140-142)

Recrystallization video (0-14:38 min)

Melting Point

Lab 4

Feb 11-17

Thin layer chromatography (TLC);
Recrystallization, cont'd.

Lab Manual pp. 33-38

Mohrig pp. 127-131, 253-254; ch. 18

TLC video


Lab 5

Feb 18-24

I. Gas chromatography: alkyl acetates mixture

II. Refractive index

I. Lab Manual pp. 39-43

Mohrig ch. 20 (except 20.8 - see Manual explanation)

GC video 1; GC video 2

II. Lab Manual pp. 45-47 (except Procedure steps 1 and 2b; Fig. 1; Table 1)

Mohrig ch. 13


Lab 6

Feb 25-Mar 2

Infrared and ultraviolet-visible spectroscopy; mass spectrometry

Lab Manual pp. 49, 53-56

Mohrig ch. 21 (21.1-21.2, 21.7-21.9); ch. 25 (pp 465-470); ch. 24


Lab 7

Mar 3-7, 16

Identification of an unknown; simple distillation to determine boiling point; IR continued

Spring Break March 9-22

Lab Manual pp. 49-51 Experiment pdf

Mohrig ch. 12 (pp 173-174, 176-183); ch. 21 (21.3-21.5, 21.10-21.11)

Simple Distillation video (0-8:41 min); IR sample prep video

GC Acetates (new Report Form)
[Ref. Index not required]

See Bb for exact due date.

Lab 8

Mar 17-23Mar 24-30


Note: Lab Week is Tues.-Mon.

Spectroscopy Assignment

Identification of Unknown

See Bb for exact due date.

Lab 9

Mar 30-Apr 4

Note: Lab Week is Mon. -Sat.
All LabFlow assignments begin on Monday for all sections.


Chemistry Math, Labware Kit Review

via LabFlow

All LabFlow work will be due the following Monday.


Lab 10

Apr 6-11


Identifying Unknowns using IR

via LabFlow Chemistry Math, Labware Kit Review

Lab 11

Apr 13-18



Identification of an Unknown Alcohol


via LabFlow Identifying Unknowns using IR

Lab 12

Apr. 20-25


Extraction of Caffeine

via LabFlow Identification of an Unknown Alcohol

Lab 13

Apr. 27-May 2

Fractional Distillation

via LabFlow

Extraction of Caffeine

Lab 14

May 5 (Tues.)-May 11 (Mon.)


Final Exam - see Bb for information
  Fractional Distillation (Due by Mon., May 4)